A monoamine oxidase inhibitor1-Hydrazinophthalazine hydrochloride is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. It acts as a non-selective MAO-A/B inhibitor and semicarbazide sensitive amine oxidase inhibitor. Further, it serves as an antihypertensive.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
A monoamine oxidase inhibitor1-Hydrazinophthalazine hydrochloride is a non-nucleoside analog that inhibits DNA methylation and reactivates the expression of tumor suppressor genes. It acts as a non-selective MAO-A/B inhibitor and semicarbazide sensitive amine oxidase inhibitor. Further, it serves as an antihypertensive.
Solubility
Soluble in water. Slightly soluble in diethyl ether and alcohol.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Kruszynska, A. T. Solid-state studies of phthalazinylhydrazones and triazolophthalazines: the role of the nitro group. CrystEngComm 2015, 17 (40), 7702-7716.
- Popov, I. D.; Levchenkov, S. I.; Shcherbakov, I. N.; Aleksandrov, G. G.; Starikova, Z. A.; Lukov, V. V.; Kogan, V. A. Molecular and crystal structure of iron(III) and nickel(II) complexes with 1'-phthalazinylhydrazones of heterocyclic carbonyl compounds. J. Struct. Chem. 2015, 56 (1), 102-107.