1,2-Benzenedimethanol is a raw material used in chemical synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
1,2-Benzenedimethanol is a raw material used in chemical synthesis.
Solubility
Soluble in water, ether, ethanol, benzene.
Notes
Store in cool, dry conditions in a sealed container. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Quan-Jing Zhu; Wei-Lin Dai; and Kang-Nian Fan. A green process for the oxidative lactonization of 1,2-benzenedimethanol by tungstic acid with aqueous H2O2. Green Chem. 2010, 12 (2), 205-208.
- Quanjing Zhu; Xiaofeng Chu; Zhaoyan Zhang; Wei-Lin Dai; Kangnian Fan. Effect of the tungsten precursor on the high activity of the WO3/ZrO2 catalyst in the oxidative lactonization of 1,2-benzenedimethanol. Applied Catalysis A: General. 2012, 435-436, 141-147.
- The 7-membered cyclic orthoformates, formed with triethyl or trimethyl orthoformate, are superior reagents for the protection of carbonyl groups as their 2,4-benzodioxepine derivatives. These can be readily cleaved in high yield by Pd-catalyzed hydrogenolysis: Tetrahedron Lett., 30, 4165 (1989); J. Am. Chem. Soc., 116, 558 (1994).
- Has also been employed for the protection of boronic acids, by reaction in THF in the presence of a dehydrating agent, e.g. Na2SO4. These derivatives can be readily cleaved by hydrogenolysis or hydrolysis: Tetrahedron Lett., 37, 6705 (1996).