1,2-Benzisoxazole derivative zonisamide is a novel antiepileptic drug and is effective for the treatment of partial seizures. 1,2-Benzisoxazole is a potential substrates of rabbit liver aldehyde oxidase. It is used to produce 5-nitro-benzo[d]isoxazole. It is involved in manufacturing medicines ( antiepileptics and antipsychotics).
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water. 4.1 mg/mL in water at 25°C
Notes
Light Sensitive. Store at 4°C. Store in the dark. Incompatible with light and oxidizing agents.
RUO – Research Use Only
D H Peters; E M Sorkin. Zonisamide. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in epilepsy. Drugs.1993, 45, (5), 760-787.
W Gristwood; K Wilson. Kinetics of some benzothiazoles, benzoxazoles, and quinolines as substrates and inhibitors of rabbit liver aldehyde oxidase. Xenobiotica.1988, 18, (8), 949-954.