Ethyl iodoacetate was used in the synthesis of trans-2,3-disubstituted indolines by reacting with 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade.
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Applications
Ethyl iodoacetate was used in the synthesis of trans-2,3-disubstituted indolines by reacting with 1-azido-2-allylbenzene derivatives via a diastereoselective radical cascade.
Solubility
Insoluble in water.
Notes
Light sensitive. Store in dark. Storage temperature is 2-8°C. Store away from oxidizing agents.
RUO – Research Use Only
François Brucelle; Philippe Renaud. Synthesis of a leucomitosane via a diastereoselective radical cascade. Journal of Organic Chemistry. 2013, 78, (12), 6245-6252.
Pier Giorgio Cozzi; Alessandro Mignogna and Paola Vicennati. Dimethylzinc-Mediated, Oxidatively Promoted Reformatsky Reaction of Ethyl Iodoacetate with Aldehydes and Ketones. Advanced Synthesis & Catalysis. 2008, 300, (7-8), 975-978.