Methyl benzenesulfonate is a sulfonate ester which acts as a potential genotoxic impurity in drug substances. Further, it exerts genotoxic effects in bacterial and mammalian cell systems.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methyl benzenesulfonate is a sulfonate ester which acts as a potential genotoxic impurity in drug substances. Further, it exerts genotoxic effects in bacterial and mammalian cell systems.
Solubility
Miscible with chloroform, methanol, ethanol and ether. Immiscible with water.
Notes
Incompatible with strong oxidizing agents, strong acids and strong bases.
RUO – Research Use Only
General References:
- Alkylating agent.
- Giricheva, N. I.; Fedorov, M. S.; Girichev, G. V. Conformations of methylbenzenesulfonate and its substituted derivatives: gas-phase electron diffraction versus vibrational spectroscopy. Struct. Chem. 2015, 26 (5), 1543-1553.
- Zhang, X.; Jiang, X.; Li, Y.; Lin, Z.; Zhang, G.; Wu, Y. Synthesis, crystal structures and properties of new quinolinium derivatives. Chem. Phys. Lett. 2015, 641, 141-145.