Pyruvic aldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists.
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Applications
Pyruvic aldehyde is used in the synthesis and cytotoxicity evaluation of N-terminal analogues of tubulysin-U an antimitotic compound. Also used in the synthesis of imidazoles as potent calcitonin gene-related CGRP antagonists.
Solubility
Soluble in DMSO, water.
Notes
Air sensitive. Store under dry inert gas. Store away from oxidizing agents, air.
RUO – Research Use Only
General References:
- Paul J Beisswenger; Keith S Drummond; Robert G Nelson; Scott K Howell; Benjamin S Szwergold; Michael Mauer. Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress. Diabetes. 2005, 54 (11), 3274-3281.
- Katrien H J Gaens; Coen D A Stehouwer; Casper G Schalkwijk. Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity. Current Opinion in Lipidology. 2013, 24 (1), 4-11.