TheraPure™ Vaccinia Capping Enzyme (100 U/μL)
TheraPure™ Vaccinia Capping Enzyme (100 U/μL)
Thermo Scientific™

TheraPure™ Vaccinia Capping Enzyme (100 U/μL)

Vaccinia Capping Enzyme efficiently adds Cap-0 structures to RNA, providing a reliable and efficient method for enhancing mRNA stability and translational efficiency in both research and large-scale mRNA production applications.
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Catalog NumberQuantity
EO16610TPB0140.5 mL
EO16610TPB0151 mL
EO16610TPB0018 mL
EO16610TPB00224 mL
Catalog number EO16610TPB014
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Quantity:
0.5 mL

Thermo Scientific TheraPure products for post-transcriptional capping are intended for use in the synthesis of mRNA in the development of mRNA therapeutics and vaccines.

Post-transcriptional capping involves adding a 5' cap structure to mRNA after transcription, enhancing mRNA stability and translation efficiency. The process uses TheraPure Vaccinia Capping Enzyme and TheraPure 2'-O-Methyltransferase for adding the cap structures and TheraPure S-Adenosyl-L-Methionine as a methyl donor. Capping efficiency can reach >95%.

Designed for process development

TheraPure Vaccinia Capping Enzyme is a highly efficient enzyme used for adding 7-methylguanylate cap structures (Cap-0) to the 5' ends of uncapped RNA. This capping is essential for the stability and translational efficiency of mRNA.

TheraPure 2'-O-Methyltransferase is a high-purity enzyme designed for the methylation of RNA molecules, specifically adding a methyl group to the 2'-O position of the ribose sugar (Cap-1).

TheraPure S-Adenosyl-L-Methionine is a high-purity reagent used as a methyl group donor in post-transcriptional capping for Cap-0 and Cap-1 structure.

These TheraPure products are essential tools in the field of molecular biology, providing researchers with reliable and high-quality enzymes and reagents to advance the development of mRNA therapeutics and vaccines.

For Research Use Only.
Specifications
Product TypeRNA Capping
Quantity0.5 mL
Shipping Condition-25°C to -15°C
Concentration100 U/μL
EnzymeVaccinia Capping Enzyme
FormLiquid
Research CategoryDrug Development
Sensitive to Heat InactivationNo
Unit SizeEach

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