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2,2-Difluorocyclopropanecarboxylic acid, 95%, Thermo Scientific Chemicals
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Catalog number H25752.06
also known as H25752-06
Price (USD)/ Each
1,370.65
Online exclusive
1523.00 Save 152.35 (10%)
-
Quantity:
5 g
Price (USD)/ Each
1,370.65
Online exclusive
1523.00 Save 152.35 (10%)
2,2-Difluorocyclopropanecarboxylic acid, 95%, Thermo Scientific Chemicals
Catalog numberH25752.06
Price (USD)/ Each
1,370.65
Online exclusive
1523.00 Save 152.35 (10%)
-
Chemical Identifiers
CAS107873-03-0
IUPAC Name2,2-difluorocyclopropane-1-carboxylic acid
Molecular FormulaC4H4F2O2
InChI KeyKMLMOVWSQPHQME-UHFFFAOYNA-N
SMILESOC(=O)C1CC1(F)F
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to very pale brown
FormCrystals or powder or crystalline powder
Assay (Aqueous acid-base Titration)≥94.0 to ≤106.0%
Assay (GC)≥94.0%
Melting Point (clear melt)59.0-65.0?C
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.
Solubility
Soluble in water.
Notes
Incompatible with strong oxidizing agents.
2,2-Difluorocyclopropanecarboxylic acid derivative (i.e. 2,2-difluorocyclopropanecarbonyl chloride) is used in Friedel-Crafts reactions with various arenes to prepare aryl 2,2-difluorocyclopropyl ketones.
Solubility
Soluble in water.
Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Dolbier, W. R.; Cornett, E.; Martinez, H.; Xu, W. Friedel-Crafts Reactions of 2,2-Difluorocyclopropanecarbonyl Chloride: Unexpected Ring-Opening Chemistry. J. Org. Chem. 2011, 76 (9), 3450-3456.
- Liu, C-H.; Wang, S-A.; Ruszczycky, M. W.; Chen, H.; Li, K.; Murakami, K.; Liu, H. Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid: Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase. Org. Lett. 2015, 17 (13), 3342-3345.