4-Cyanopiperidine is used as an intermediate for the preparation of pharmaceutical substances like antidepressants and anti-inflammatory. It is used as a precursor for the synthesis of piperidine derivatives.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Cyanopiperidine is used as an intermediate for the preparation of pharmaceutical substances like antidepressants and anti-inflammatory. It is used as a precursor for the synthesis of piperidine derivatives.
Solubility
Soluble in chloroform.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Tran, L. D.; Roane, J.; Daugulis, O. Directed Amination of Non-Acidic Arene C[BOND]H Bonds by a Copper-Silver Catalytic System. Angew. Chem. Int. Ed. 2013, 52 (23), 6043-6046.
- Woo, H. M.; Lee, Y. S.; Roh, E. J.; Seo, S. H.; Song, C. M.; Chung, H. J.; Pae, A. N.; Shin, K. J. Synthesis and biological evaluation of 4-piperidinecarboxylate and 4-piperidinecyanide derivatives for T-type calcium channel blockers. Bioorg. Med. Chem. Lett. 2011, 21 (19), 5910-5915.