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1,2,2,6,6-Pentamethylpiperidine, 97%, Thermo Scientific Chemicals
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Catalog number H27729.06
also known as H27729-06
Price (USD)/ Each
98.70
-
Quantity:
5 g
Price (USD)/ Each
98.70
1,2,2,6,6-Pentamethylpiperidine, 97%, Thermo Scientific Chemicals
Catalog numberH27729.06
Price (USD)/ Each
98.70
-
Chemical Identifiers
CAS79-55-0
IUPAC Name1,2,2,6,6-pentamethylpiperidin-1-ium
Molecular FormulaC10H22N
InChI KeyXULIXFLCVXWHRF-UHFFFAOYSA-O
SMILESC[NH+]1C(C)(C)CCCC1(C)C
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Clear colorless to pale yellow
Refractive Index1.4570-1.4620 @ 20?C
Identification (FTIR)Conforms
FormLiquid
Assay (GC)≥96.0%
Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine's ED50 4.7-fold.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.
Solubility
Soluble in toluene, dimethylformamide.
Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.
Pharmacological evaluation of the antagonism of nicotine′s central effects by mecamylamine and pempidine where pempidine was found to increase the ED50 of nicotine (0.73 mg/kg) for depression of spontaneous activity in a dose-related manner. At a dose of 3 mg/kg, pempidine increased nicotine′s ED50 4.7-fold.
Solubility
Soluble in toluene, dimethylformamide.
Notes
Air Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, air.
RUO – Research Use Only
General References:
- T J Martin,; J Suchocki,; E L May,; B R Martin. Pharmacological evaluation of the antagonism of nicotine's central effects by mecamylamine and pempidine. JPET. 1994, 254 (1), 45-51.
- authors. title . Journal name. year of publication , volume issue , pg no.