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2,5-Dichloro-4-(trifluoromethyl)pyridine, 97%, Thermo Scientific Chemicals
Catalog number H33442.03
also known as H33442-03
Price (USD)/ Each
174.65
Online exclusive
194.00 Save 19.35 (10%)
-
Quantity:
1 g
Price (USD)/ Each
174.65
Online exclusive
194.00 Save 19.35 (10%)
2,5-Dichloro-4-(trifluoromethyl)pyridine, 97%, Thermo Scientific Chemicals
Catalog numberH33442.03
Price (USD)/ Each
174.65
Online exclusive
194.00 Save 19.35 (10%)
-
Chemical Identifiers
CAS89719-92-6
Specifications
Specification Sheet
Specification SheetAssay (GC)≥96.0%
FormLiquid
Refractive Index1.4790-1.4840 @ 20?C
Appearance (Color)Clear pale yellow
2-chloro-6-(trifluoromethyl)pyridine, 2-chloro-5-(trifluoromethyl)pyridine and 3-chloro-4-(trifluoromethyl)pyridine were each converted into the three possible carboxylic acids 2, 4, 6,8, 10, 12, 16, 17 and 20. This was achieved by employing several, but not all of the organometallic toolbox methods : transformation of a more basic organometallic species into a less basic isomer by transmetalation-equilibration.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-chloro-6-(trifluoromethyl)pyridine, 2-chloro-5-(trifluoromethyl)pyridine and 3-chloro-4-(trifluoromethyl)pyridine were each converted into the three possible carboxylic acids 2, 4, 6,8, 10, 12, 16, 17 and 20. This was achieved by employing several, but not all of the organometallic “toolbox methods”: transformation of a more basic organometallic species into a less basic isomer by transmetalation-equilibration.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, aluminum. Protection under nitrogen and lower temperature is recommended(below 4 deg C).
2-chloro-6-(trifluoromethyl)pyridine, 2-chloro-5-(trifluoromethyl)pyridine and 3-chloro-4-(trifluoromethyl)pyridine were each converted into the three possible carboxylic acids 2, 4, 6,8, 10, 12, 16, 17 and 20. This was achieved by employing several, but not all of the organometallic “toolbox methods”: transformation of a more basic organometallic species into a less basic isomer by transmetalation-equilibration.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, aluminum. Protection under nitrogen and lower temperature is recommended(below 4 deg C).
RUO – Research Use Only
General References:
- Florence Mongin,; Antonio Tognini,; Fabrice Cottet,; Manfred Schlosses. Halogen shuffling in pyridines: Site selective electrophilic substitutions of 2-chloro-6-(trifluoromethyl)pyridine. Tetrahedron Letters. 1998, 39(13), 1749-1752.
- Fabrice Cottet,; Marc Marull,; Olivier Lefebvre,; Manfred Schlosser. Recommendable Routes to Trifluoromethyl-Substituted Pyridine- and Quinolinecarboxylic Acids. European Journal of Organic Chemistry. 2003, 81559-1568,.