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2-Aminopyridine-6-methanol, 97%, Thermo Scientific Chemicals
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Catalog number H33485.03
also known as H33485-03
Price (USD)/ Each
210.00
-
Quantity:
1 g
Price (USD)/ Each
210.00
2-Aminopyridine-6-methanol, 97%, Thermo Scientific Chemicals
Catalog numberH33485.03
Price (USD)/ Each
210.00
-
Chemical Identifiers
CAS79651-64-2
IUPAC Name(6-aminopyridin-2-yl)methanol
Molecular FormulaC6H8N2O
InChI KeyYGMPMXTWKROXPP-UHFFFAOYSA-N
SMILESNC1=CC=CC(CO)=N1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)Pale brown
Melting Point (clear melt)85.0-95.0?C
Assay (GC)≥96.0%
FormPowder
4-Aminopyridine (4-AP), a well-known potassium channel blocker, has been shown to enhance conduction in injured and demyelinated axons. Aminopyridine has a narrow therapeutic range in clinical application. In the current study, we investigated whether AP-MeOH can enhance impulse conduction in an animal model of MS.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Slightly soluble.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
Slightly soluble.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Jinfeng Zhao,; Peng Song,; Yanling Cui,; Xuemei Liu,; Shaowu Sun,; Siyao Hou,; Fengcai Ma. Effects of hydrogen bond on 2-aminopyridine and its derivatives complexes in methanol solvent. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2015, 131 282-287.
- Gary Leung,; Wenjing Sun,; Sarah Brookes,; Daniel Smith,; Riyi Shi. Potassium channel blocker, 4-aminopyridine-3-methanol, restores axonal conduction in spinal cord of an animal model of multiple sclerosis. Experimental Neurology. year of publication , 227 (1), 232-235.