Search Thermo Fisher Scientific
Element Search
Structure SearchThermo Scientific Chemicals
3,3',5-Triiodo-L-thyronine, 95%, Thermo Scientific Chemicals
Catalog number: H34068.MD
250 mg, Each
Thermo Scientific Chemicals
3,3',5-Triiodo-L-thyronine, 95%, Thermo Scientific Chemicals
Catalog number: H34068.MD
250 mg, Each
Quantity
Catalog number: H34068.MD
also known as H34068-MD
Price (USD)
91.80
Each
Quantity
-
Have Questions?
Chemical Identifiers
CAS
6893-02-3
IUPAC Name
2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
Molecular Formula
C15H12I3NO4
InChI Key
AUYYCJSJGJYCDS-UHFFFAOYNA-N
SMILES
NC(CC1=CC(I)=C(OC2=CC=C(O)C(I)=C2)C(I)=C1)C(O)=O
Specifications
Specification SheetAppearance (Color)
White
Comment
Material sourced in the U.S. and in other countries
Optical Rotation
29.5 ± 1° (C=4.75 in 1M HCl: EtOH 1:2, U.S. sourced material)
Form
Powder
Optical Rotation
23.9 ± 0.1° (C=1 in 1M HCl/Ethanol 1:2, non-U.S. sourced material)
Description
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3'-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3?,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3′, 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3′, 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3′-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3′,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.
Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.
Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.
Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3′, 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3′, 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and was shown to be saturable, reversible, and stereospecific. A fluorescent derivative of the thyroid hormone 3,3′-triiodo-L-thyronine binds to cultured mouse fibroblasts; such binding is saturable. 3,3′,5-Triiodo-L-thyronine Up-regulation of Na,K-ATPase Activity and Cell Surface Expression in Alveolar Epithelial Cells Is Src Kinase- and Phosphoinositide 3-Kinase-dependent.
Solubility
Insoluble in water, ethanol and propylene glycol. Soluble in dilute alkalies.
Notes
Light Sensitive. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, Strong bases, light.
RUO – Research Use Only
Figures
Documents & Downloads
Certificates
Search by lot number or partial lot number
Frequently asked questions (FAQs)
Citations & References
Search citations by name, author, journal title or abstract text