Thermo Scientific Chemicals

4-Trifluoromethyl-1H-pyrazole, 97%, Thermo Scientific Chemicals

Catalog number: H34396.03
1 g, Each
Thermo Scientific Chemicals

4-Trifluoromethyl-1H-pyrazole, 97%, Thermo Scientific Chemicals

Catalog number: H34396.03
1 g, Each
Quantity
Catalog number: H34396.03
also known as H34396-03
Price (USD)
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Chemical Identifiers

CAS
52222-73-8
IUPAC Name
4-(trifluoromethyl)-1H-pyrazole
Molecular Formula
C4H3F3N2
InChI Key
KDEJQUNODYXYBJ-UHFFFAOYSA-N
SMILES
FC(F)(F)C1=CNN=C1
Appearance (Color)
White to yellow to orange
Form
Crystals or powder or crystalline powder
Assay (GC)
≥96.0%

Description

It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediates. The palladium-catalyzed cross-coupling reactions of 5-tributylstannyl-4-fluoro-1H-pyrazole with aryl iodides provided high yields of the corresponding 5-aryl-4-fluoro-1H-pyrazoles.

Notes
Incompatible with strong oxidizing agents. Store at room temperature.
RUO – Research Use Only

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