2-Cyanobenzoic acid has been used as reactant in the synthesis of T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives, Benzoate modified β-cyclodextrin derivatives and Pyrrolo[1,2-f]triazines for use as JAK2 inhibitors. As a reactant involved in decarboxylation, decarboxylative halogenation and protodecarboxylation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Cyanobenzoic acid has been used as reactant in the synthesis of T-box riboswitch antiterminator RNA-binding oxazolidinone derivatives, Benzoate modified β-cyclodextrin derivatives and Pyrrolo[1,2-f]triazines for use as JAK2 inhibitors. As a reactant involved in decarboxylation, decarboxylative halogenation and protodecarboxylation.
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.
RUO – Research Use Only
Anlai Wang; John A.Maguire; Ed Biehl. Preparation of 2-cyanobenzoic acids from the reaction of bromobenzoic acids with arylacetonitriles and LDA. J. Org. Chem. 1998, 63, (8),2451-2455
Dacio Adhemar Iglesias; Danila Lujan Ruiz; Patricia Ercilia Allegretti. Experimental study of tautomeric equilibria of 2-cyanobenzoic acids in gas, solution and solid phase. Journal of Applied Solution Chemistry and Modeling. 2012, 1, 113-120