Cyclohexylmagnesium chloride is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). It is used as a reagent for the introduction of the cyclohexyl group; metalation of CH-acidic compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Cyclohexylmagnesium chloride is used as a Grignard reagent in greener solvent, 2-methyltetrahydrofuran (2-MeTHF). It is used as a reagent for the introduction of the cyclohexyl group; metalation of CH-acidic compounds.
Solubility
It reacts violently with water.
Notes
Air & moisture sensitive. Incompatible with oxidizing agents.
RUO – Research Use Only
Yoshio Okamoto; Koji Ohta; Heimei Yuki. Asymmetric-selective polymerization of (RS)-α-methylbenzyl methacrylate with the cyclohexylmagnesium chloride-(---)- Sparteine system in toluene at -78°C. Macromolecules. 1978, 11, (4),724-727
Jinhwa Lee; Heejin Kim; Jin Kun Cha. A new variant of the kulinkovich hydroxycyclopropanation. Reductive coupling of carboxylic esters with terminal olefins. J. Am. Chem. Soc. 1996, 118, (17),4198-4199