It can be heated to produce 2-trifluoromethyl-3H-quinazoline-4-thione in the presence of reagent molecular sieves and solvent CHCl3 with reaction time of 2 hours. It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It can be heated to produce 2-trifluoromethyl-3H-quinazoline-4-thione in the presence of reagent molecular sieves and solvent CHCl3 with reaction time of 2 hours. It is an important organic intermediate used in agrochemicals, pharmaceuticals and dyestuff fields.
Solubility
Slightly soluble in water.
Notes
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.
RUO – Research Use Only
General References:
- Chia-Yang Shiau, et al. Reactions of 2-aminothiobenzamide with isocyanates: a new synthesis of 2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-one and 3,4-dihydro-2H-pyrimido[1,2-c]quinazolin-6(7H)-one. J. Heterocycl. Chem.,1989,26(3), 595-596.
- R. Morrin Acheson, et al. Synthesis and X-ray crystal structures of 2,3-dihydro-2-mercapto-2,1,3-benzophosphadiazine-4(1H)-thione 2-sulphide derivatives.J. Chem. Soc., Perkin Trans. 2,1985,(12), 1913-1917.