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Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water, Thermo Scientific Chemicals
Catalog number: H51864.AA
5 mL, Each
Thermo Scientific Chemicals
Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water, Thermo Scientific Chemicals
Catalog number: H51864.AA
5 mL, Each
Quantity
Catalog number: H51864.AA
also known as H51864-AA
Price (USD)
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48.65 51.65 Online priceSave 3.00 (5%)
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Each
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Chemical Identifiers
CAS
51805-45-9
IUPAC Name
3-[bis(2-carboxylatoethyl)phosphanyl]propanoate
Molecular Formula
C9H12O6P
InChI Key
PZBFGYYEXUXCOF-UHFFFAOYSA-K
SMILES
[O-]C(=O)CCP(CCC([O-])=O)CCC([O-])=O
Specifications
Specification SheetAssay (Aqueous acid-base Titration)
0.45M - 0.55M
Description
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.
Solubility
Miscible with water and methanol.
Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents
Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization process for RNA isolation. It acts as a chelating agent and forms complexes with various heavy metal ions such as Zn(II), Cd(II), Pb(II), and Ni(II). Furthermore, it is useful in the labeling of cysteine residues with maleimides.
Solubility
Miscible with water and methanol.
Notes
Air sensitive. Store in cool place. Incompatible with strong oxidizing agents
RUO – Research Use Only
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