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3-Bromo-1-trimethylsilyl-1-propyne, 98%, Thermo Scientific Chemicals
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Catalog number H53451.06
also known as H53451-06
Price (USD)/ Each
88.65
Online exclusive
97.90 Save 9.25 (9%)
-
Quantity:
5 g
Price (USD)/ Each
88.65
Online exclusive
97.90 Save 9.25 (9%)
3-Bromo-1-trimethylsilyl-1-propyne, 98%, Thermo Scientific Chemicals
Catalog numberH53451.06
Price (USD)/ Each
88.65
Online exclusive
97.90 Save 9.25 (9%)
-
Chemical Identifiers
CAS38002-45-8
IUPAC Name(3-bromoprop-1-yn-1-yl)trimethylsilane
Molecular FormulaC6H11BrSi
InChI KeyGAPRPFRDVCCCHR-UHFFFAOYSA-N
SMILESC[Si](C)(C)C#CCBr
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Specifications
Specification Sheet
Specification SheetAssay (HPLC)97.5% min
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.
Solubility
Immiscible with water.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
3-Bromo-1-trimethylsilyl-1-propyne is used in the preparation of tetrahydroisoquinoline-3-carboxylic acid derivatives. It acts as a propargylating agent and used for the alkylation of dianion of beta-keto esters at gamma-carbon. It plays an important role in the synthesis of allenic alcohols and terminal conjugated enynes.
Solubility
Immiscible with water.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Wanat, P.; Walczak, S.; Wojtczak, B. A.; Nowakowska, M.; Jemielity, J.; Kowalska, J. Ethynyl, 2-Propynyl, and 3-Butynyl C-Phosphonate Analogues of Nucleoside Di- and Triphosphates: Synthesis and Reactivity in CuAAC. Org. Lett. 2015, 17 (12), 3062-3065.
- Guo, T.; Liu, Y.; Li, B.; Liu, H. Convenient synthesis of α,α-(bisallyl and bispropargyl)-substituted amines via aza-Barbier-type reaction. Tetrahedron Lett. 2015, 56 (19), 2469-2471.