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4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester, 98+%, Thermo Scientific Chemicals
Catalog number: H54402.MC
100 mg, Each
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Thermo Scientific Chemicals
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester, 98+%, Thermo Scientific Chemicals
Catalog number: H54402.MC
100 mg, Each
Quantity
Catalog number: H54402.MC
also known as H54402-MC
Price (USD)
175.00
Each
Quantity
-
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Chemical Identifiers
CAS
146998-31-4
IUPAC Name
2,5-dioxopyrrolidin-1-yl 4-{2-[4-(dimethylamino)phenyl]diazen-1-yl}benzoate
Molecular Formula
C19H18N4O4
InChI Key
IBOVDNBDQHYNJI-UHFFFAOYSA-N
SMILES
CN(C)C1=CC=C(C=C1)N=NC1=CC=C(C=C1)C(=O)ON1C(=O)CCC1=O
Specifications
Specification SheetAssay (HPLC)
>98.0%
Description
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.
Solubility
Soluble in DMSO.
Notes
Moisture sensitive. Incompatible with oxidizing agents and heat.
4-[4-(Dimethylamino)phenylazo]benzoic acid N-succinimidyl ester is a useful reagent (similar to MANCYL-SE) for labeling proteins or peptides through their amino-groups by forming stable peptide bonds. The succinimidyl ester is reactive with terminal amines or lysines of peptides and other nucleophiles for fluorescent studies of proteins. Its fluorescent properties (has a characteristic broad and intense visible absorption but has no fluorescence) make it an ideal long wavelength quencher and it has been utilized as an acceptor chromophore in FRET studies. It is also used for N-terminal modification of peptides in automated synthesis.
Solubility
Soluble in DMSO.
Notes
Moisture sensitive. Incompatible with oxidizing agents and heat.
RUO – Research Use Only
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