4-(Aminomethyl)indole is used as a reactant for preparation of dopamine receptor antagonists and for preparation of high-affinity ligands to α2δ subunit of voltage-gated calcium channels. It is used as a synthetic intermediate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-(Aminomethyl)indole is used as a reactant for preparation of dopamine receptor antagonists and for preparation of high-affinity ligands to α2δ subunit of voltage-gated calcium channels. It is used as a synthetic intermediate.
Solubility
Soluble in ethanol, dimethyl sulfoxide and dimethyl formamide.
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- G. P. Zhikhareva.; S. A. Rabinovich.; E. V. Maksakovskaya.; N. R. Dadasheva.; M. N. Lebedeva.; N. P. Kozyreva.; Vu. Tkhi Tuet.; Din Van Shi.; A. M. Shcherbakov. Synthesis and antimalarial activity of 2-styryl-4-(δ-diethylamino-α-methylbutylamino)-7-chloroquinazolines. Pharmaceutical Chemistry Journal. 1990, 24 (10), 743-749.
- M. V. Mezentseva.; I. S. Nikolaeva.; E. A. Golovanova.; A. N. Fomina. Synthesis and antiviral activity of 2-anilinomethyl derivatives of 5-hydroxyindole. Pharmaceutical Chemistry Journal. 1990, 24 (10), 749-751.