Methyl methanesulfonate is a DNA adduct that adds methyl groups to Dan at 7-guanine, 3-guanine and 3-adenine.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Methyl methanesulfonate is a DNA adduct that adds methyl groups to Dan at 7-guanine, 3-guanine and 3-adenine.
Solubility
Very soluble in water.
Notes
Store at room temperature with proper ventilation. Keep away from oxidizing agents.
RUO – Research Use Only
General References:
- D. Segerbäck.; C.J. Calleman.; L. Ehrenberg.; G. Löfroth.; S. Osterman-Golkar. Evaluation of genetic risks of alkylating agents IV. Quantitative determination of alkylated amino acids in haemoglobin as a measure of the dose after treatment of mice with methyl methanesulfonate. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 1978, 49 (1),71-82.
- William F. Morgan.; James E. Cleaver. 3-Aminobenzamide synergistically increases sister-chromatid exchanges in cells exposed to methyl methanesulfonate but not to ultraviolet light .Mutation Research Letters. Mutation Research Letters, 104 (6),361-366.