2,4-Dichloro-5-methylpyrimidine, 98%, Thermo Scientific Chemicals
2,4-Dichloro-5-methylpyrimidine, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

2,4-Dichloro-5-methylpyrimidine, 98%, Thermo Scientific Chemicals

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Quantity:
1 g
5 g
Catalog number H55206.03
also known as H55206-03
Price (USD)/ Each
53.20
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Quantity:
1 g
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2,4-Dichloro-5-methylpyrimidine, 98%, Thermo Scientific Chemicals
Catalog numberH55206.03
Price (USD)/ Each
53.20
-
Add to cart
Chemical Identifiers
CAS1780-31-0
IUPAC Name2,4-dichloro-5-methylpyrimidine
Molecular FormulaC5H4Cl2N2
InChI KeyDQXNTSXKIUZJJS-UHFFFAOYSA-N
SMILESCC1=CN=C(Cl)N=C1Cl
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SpecificationsSpecification SheetSpecification Sheet
Appearance (Color)Clear colorless to pale yellow
Assay (unspecified)≥97.5%
FormLiquid or solid, low melting solid
2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2,4-Dichloro-5-methylpyrimidine, is used in the synthesis of (2-chloro-6-methyl-pyrimidin-4-yl)-(2,3-dihydro-benzothiazol-6-yl)-amine. It can react with piperidineto produce 2-chloro-5-methyl-4-piperidin-1-yl-pyrimidine. This reaction will need solvent dioxane.

Solubility
Soluble in chloroform, ether, ethyl acetate and toluene

Notes
Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only

General References:

  1. Henry C. Koppel.; Robert Henre Springer.; Roland K. Robins.; C. C. Cheng. Pyrimidines. V. Analogs of 2-(o-Chlorobenzylthio)-4-dimethylamino- 5-methylpyrimidine (Bayer DG-428)1. J. Org. Chem. 1962, 27, 91), 181-185.
  2. Bryan W. Roberts.; Joseph B. Lambert.; John D. Roberts. Nitrogen-15 Magnetic Resonance Spectroscopy. VI. Pyrimidine Derivatives1,2. J. Am. Chem. Soc. 1965, 87, (23), 5439-5441.