di-2-Pyridyl ketone has been used in the preparation of unusual {Ni(II)(3)Ln(III)(?-OR)(6)}(3+) complexes with a star topology. Its monoanionic form has been used in the synthesis of triangular Ni(2)M (M = lanthanide, Y) complexes. The Schiff base ligands derived from di-2-pyridyl ketone exhibit ant proliferative activity in SK-N-MC neuroepithelioma (cancer) cells.
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Applications
di-2-Pyridyl ketone has been used in the preparation of unusual {Ni(II)(3)Ln(III)(μ-OR)(6)}(3+) complexes with a “star” topology. Its monoanionic form has been used in the synthesis of triangular Ni(2)M (M = lanthanide, Y) complexes. The Schiff base ligands derived from di-2-pyridyl ketone exhibit ant proliferative activity in SK-N-MC neuroepithelioma (cancer) cells.
Solubility
Low solubility in water.
Notes
Desiccate at room temperature. Keep away from oxidizing agents.
RUO – Research Use Only
General References:
- Varughese Philipa.; V Suni.; Maliyeckal R Prathapachandra Kurup.; Munirathinam Nethaji. Structural and spectral studies of nickel(II) complexes of di-2-pyridyl ketone N4,N4-(butane-1,4-diyl) thiosemicarbazone. Polyhedron. 2004, 23 (7),1225-1233.
- Paul V. Bernhardt.; Lorraine M. Caldwell.; Timothy B.; Chaston, Piao Chin.; Des R. Richardson. Cytotoxic iron chelators: characterization of the structure, solution chemistry and redox activity of ligands and iron complexes of the di-2-pyridyl ketone isonicotinoyl hydrazone (HPKIH) analogues. J. Biol. Inorg. Chem. 2003, 8 (8),866-880.