tert-Butyl phenyl carbonate is used in determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography. It is also used in the synthesis of 2-nitroindoles and as a reagent for mono-Boc protection of α,ω-diamines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
tert-Butyl phenyl carbonate is used in determination of octanol-water partition coefficients by microemulsion electrokinetic chromatography. It is also used in the synthesis of 2-nitroindoles and as a reagent for mono-Boc protection of α,ω-diamines.
Solubility
Slightly soluble in water.
Notes
Keep container tightly sealed. Store in refrigerated conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- John W. Scott.; David Parker.; David R. Parrish. Improved Syntheses of Nε-Tert-butyloxycarbonyl-L-lysine and Nα-Benzyloxycarbonyl-Nε-tert-butyloxycarbonyl-I-lysine. Synthetic Communications: An International Journal for Rapid Communication of Synthetic Organic Chemistry. 1981, 11 (4), 303-314.
- Jesper ostergaard.; Steen Honoré Hansen.; Claus Larsen.; Christian Schou.; Niels H H Heegaard. Determination of octanol-water partition coefficients for carbonate esters and other small organic molecules by microemulsion electrokinetic chromatography. Electrophoresis. 2003, 24 (6), 1038-1046.