2-Amino-6-chloropyrazine is used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Amino-6-chloropyrazine is used in the preparation of A2B adenosine receptor antagonists and other biologically active compounds.
Solubility
Soluble in dimethyl sulfoxide and methanol.
Notes
Store in cool, well ventilated area. Keep container tightly closed. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Paul J. J. Colbon; Alison C. Foster; Melvyn E. Giles; Zakariya Patel; and John T. Singleton. A general and efficient route to 6-methyl-pyrazin-2-yl-amines: Alkylation of 2,6-dichloropyrazine via malonate derivatives. Journal of Heterocyclic Chemistry. 2008, 45(5), 1451-1456.
- Wisterowicz K; Foks H; Janowiec M; Zwolska-Kwiek Z. Studies on pyrazine derivatives. XXVI. Synthesis and tuberculostatic activity of N-pyrazinylthiourea. Acta Poloniae Pharmaceutica. 1989, 46(2), 101-113.