(S)-(-)-Glycidol, 99+%, ee 99+%, Thermo Scientific Chemicals
(S)-(-)-Glycidol, 99+%, ee 99+%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

(S)-(-)-Glycidol, 99+%, ee 99+%, Thermo Scientific Chemicals

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Catalog number H63502.03
also known as H63502-03
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(S)-(-)-Glycidol, 99+%, ee 99+%, Thermo Scientific Chemicals
Catalog numberH63502.03
Price (USD)/ Each
34.40
-
Add to cart
Chemical Identifiers
CAS60456-23-7
IUPAC Name[(2R)-oxiran-2-yl]methanol
Molecular FormulaC3H6O2
InChI KeyCTKINSOISVBQLD-GSVOUGTGSA-N
SMILESOC[C@@H]1CO1
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SpecificationsSpecification SheetSpecification Sheet
FormLiquid
Appearance (Color)Colorless to yellow
Assay (GC)≥99%
Enantiomeric excessChiral GC: ≥99%
(S)-(-)-Glycidol is employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis. Also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
(S)-(-)-Glycidol is employed in the synthesis of chiral (E)-allylic alcohol side-chains for introduction into prostacyclin and prostaglandin frameworks by cross-metathesis. Also used as a starting reagent to synthesize non-peptidic HIV protease inhibitors.

Solubility
Soluble in chloroform, DMSO and methanol.

Notes
Store in freezer at(-20°C). Keep container tightly closed. Store away from oxidizing agent.
RUO – Research Use Only

General References:

  1. Neil A Sheddan; Johann Mulzer. Cross metathesis as a general strategy for the synthesis of prostacyclin and prostaglandin analogues. Organic Letters. 2006, 8(14), 3101-3104.
  2. Haines TD; Adlaf KJ; Pierceall RM, et al. Direct Determination of MCPD Fatty Acid Esters and Glycidyl Fatty Acid Esters in Vegetable Oils by LC-TOFMS. J. Am. Oil Chem. Soc. 2011, 88(1), 1-14.