It is used in synthetic chemistry as an alkylating agent. Also used as a reagent in the synthesis of (R)-(+)-Lasiodiplodin, a macrolide that exhibits potent antileukemic activity against human tumors.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
It is used in synthetic chemistry as an alkylating agent. Also used as a reagent in the synthesis of (R)-(+)-Lasiodiplodin, a macrolide that exhibits potent antileukemic activity against human tumors.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
Kuo-Hsiung Leet; Nanao Hayashi; Masayoshi Okano; Iris H. Hall; Rong-Yang Wu; Andrew T. Mcphailti. Lasiodiplodin, a potent antileukemic macrolide from Euphorbia splendens. Org. Lett. 198221(5), 1119-1121.
Lúcio P. L. Logrado; Dâmaris Silveira; Luiz A. S. Romeiro; Manoel O. de Moraes; Bruno C. Cavalcanti; Letícia V. Costa-Lotufo; Cláudia do Ó Pessoa; Maria Lucilia dos Santos. Synthesis and Biological Evaluation of New Salicylate Macrolactones from Anacardic Acids. J. Braz. Chem. Soc. 200516(16a), 1217-1225.