Reactant for: preparation of inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents, N-Methylation reactions of the pyridyl group, Palladium catalyzed amination reactions, intramolecular Heck reactions, Coupling reactions and Synthesis of trisubstituted pyrimidines from polyhalopyrimidines via Suzuki coupling.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Reactant for: preparation of inhibitors of ataxia telangiectasia mutated and Rad3 related (ATR) protein kinase as potential anticancer agents, N-Methylation reactions of the pyridyl group, Palladium catalyzed amination reactions, intramolecular Heck reactions, Coupling reactions and Synthesis of trisubstituted pyrimidines from polyhalopyrimidines via Suzuki coupling.
Solubility
Slightly soluble in water.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
Minoru Ishikura; Tsukasa Ohta; Masanao Terashima. A Novel Synthesis of 4-Aryl-and 4-Heteroarylpyridines via Diethyl (4-pyridyl) borane. Chemical and Pharmaceutical Bulletin.1985 33(11), 4755-4763.
Antonio Guarna; Ernesto G. Occhiato; Fabrizio Machetti; and Vittoria Giacomellia.19-Nor-10-azasteroids. 5.1 A Synthetic Strategy for the Preparation of (+)-17-(3-Pyridyl)-(5β)-10-azaestra-1,16- dien-3-one, a Novel Potential Inhibitor for Human Cytochrome P45017α (17α-Hydroxylase/C17,20-lyase). J. Org. Chem. 1999 64(13),4985-4989.