Glycidyl (S)-(+)-3-nitrobenzenesulfonate, 98%, Thermo Scientific Chemicals
Glycidyl (S)-(+)-3-nitrobenzenesulfonate, 98%, Thermo Scientific Chemicals
Thermo Scientific Chemicals

Glycidyl (S)-(+)-3-nitrobenzenesulfonate, 98%, Thermo Scientific Chemicals

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5 g
25 g
Catalog number H64289.06
also known as H64289-06
Price (USD)/ Each
82.10
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Quantity:
5 g
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Price (USD)/ Each
82.10
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Glycidyl (S)-(+)-3-nitrobenzenesulfonate, 98%, Thermo Scientific Chemicals
Catalog numberH64289.06
Price (USD)/ Each
82.10
-
Add to cart
Chemical Identifiers
CAS115314-14-2
IUPAC Name[(2S)-oxiran-2-yl]methyl 3-nitrobenzene-1-sulfonate
Molecular FormulaC9H9NO6S
InChI KeyAIHIHVZYAAMDPM-QMMMGPOBSA-N
SMILES[O-][N+](=O)C1=CC=CC(=C1)S(=O)(=O)OC[C@@H]1CO1
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SpecificationsSpecification SheetSpecification Sheet
Assay (GC)>97.5%
Glycidyl (S)-(+)-3-nitrobenzenesulfonate is used in the synthesis of enantiopure bisoprolol by reacting with phenols using cesium fluoride as catalyst. It is also involved in the preparation of orally active HIV-1 protease inhibitor.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Glycidyl (S)-(+)-3-nitrobenzenesulfonate is used in the synthesis of enantiopure bisoprolol by reacting with phenols using cesium fluoride as catalyst. It is also involved in the preparation of orally active HIV-1 protease inhibitor.

Solubility
Soluble in chloroform, methylene chloride and tetrahydrofuran. Insoluble in hexane.

Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only

General References:

  1. Lee, S.; An, H.; Chang, D. J.; Jang, J.; Kim, K.; Sim, J.; Lee, J.; Suh, Y. G. Total synthesis of (-)-deguelin via an iterative pyran-ring formation strategy. Chem. Commun. 2015, 51 (43), 9026-9029.
  2. Iwahashi, M.; Shimabukuro, A.; Onoda, T.; Matsunaga, Y.; Okada, Y.; Matsumoto, R.; Nambu, F.; Nakai, H.; Toda, M. Discovery of selective indole-based prostaglandin D2 receptor antagonist. Bioorg. Med. Chem. 2011, 19 (15), 4574-4588.