Thermo Scientific Chemicals

3-Amino-2-hydroxypyridine, 98%, Thermo Scientific Chemicals

Catalog number: H64480.03
1 g, Each
Thermo Scientific Chemicals

3-Amino-2-hydroxypyridine, 98%, Thermo Scientific Chemicals

Catalog number: H64480.03
1 g, Each
Quantity
Catalog number: H64480.03
also known as H64480-03
Price (USD)
Quantity
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Chemical Identifiers

CAS
33630-99-8
IUPAC Name
3-amino-1,2-dihydropyridin-2-one
Molecular Formula
C5H6N2O
InChI Key
VTSFNCCQCOEPKF-UHFFFAOYSA-N
SMILES
NC1=CC=CNC1=O
Assay (HPLC)
>97.5%

Description

It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
It is used as pharmaceutical intermediate. It is involved in synthesis of functionalized pyrido[4,3-b][1,4]oxazine and imidazo[1,2-a]pyridine derivatives. The use of ethyl 2-chloro-3-oxopropanoate with 2-amino-3-hydroxypyridine or 3-amino-4-hydroxypyridine led, respectively, to imidazo[1,2-a]pyridine derivatives or ethyl pyrido[4,3-b][1,4] oxazine-2-carboxylate.

Solubility
Slightly soluble in water.

Notes
Store in cool dry place. Keep container tightly closed. Incompatible with oxidizing agents.
RUO – Research Use Only

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