2-Bromo-5-hydroxybenzaldehyde is a useful reactant used in the synthesis of PDE4 inhibitors, BCL-XL and cancel cell growth inhibitors. Also an reactant used in the preparation of many pharmaceutical agents.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Bromo-5-hydroxybenzaldehyde is a useful reactant used in the synthesis of PDE4 inhibitors, BCL-XL and cancel cell growth inhibitors. Also an reactant used in the preparation of many pharmaceutical agents.
Solubility
Soluble in chloroform, dichloromethane and ethyl acetate.
Notes
Store in cool, dry place in tightly closed container. With adequate ventilation. Store away from oxidizing agent.
RUO – Research Use Only
General References:
- Hassan M. Shallal; Jesika S. Faridi; Wade A. Russu. Anti-tumor pyrimidinylpiperazines bind to the prosurvival Bcl-2 protein family member Bcl-XL. Bioorganic & Medicinal Chemistry Letters.2011 21(5), 1325-1328.
- Yong-Kang Zhang; Jacob J. Plattner; Tsutomu Akama; Stephen J. Baker; Vincent S. Hernandez; Virginia Sanders; Yvonne Freunda, Richard Kimura; Wei Bu; Karin M. Hold; Xiao-Song Lu. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorganic & Medicinal Chemistry Letters.2011 20(7), 2270-2274.