Alcian Blue 8GX
Thermo Scientific Chemicals

Alcian Blue 8GX

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Quantity:
100 g
10 g
25 g
Catalog number J60122.22
also known as J60122-22
Price (USD)/ Each
503.65
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559.00 
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Quantity:
100 g
Request bulk or custom format
Price (USD)/ Each
503.65
Online exclusive
559.00 
Save 55.35 (10%)
Add to cart
Alcian Blue 8GX
Catalog numberJ60122.22
Price (USD)/ Each
503.65
Online exclusive
559.00 
Save 55.35 (10%)
-
Add to cart
Chemical Identifiers
CAS33864-99-2
IUPAC Name(9Z,18Z,26Z,35Z)-4,14,22,32-tetrakis({[(dimethylamino)(dimethyliminiumyl)methyl]sulfanyl}methyl)-9,18,27,36,37,39,40,41-octaaza-38-cupradecacyclo[17.17.3.1¹⁰,¹⁷.1²⁸,³⁵.0²,⁷.0⁸,³⁷.0¹¹,¹⁶.0²⁰,²⁵.0²⁶,³⁹.0²⁹,³⁴]hentetraconta-1,3,5,7,9,11(16),12,14,17(41),18,20,22,24,26,28(40),29(34),30,32,35-nonadecaene-38,38-bis(ylium) tetrachloride
Molecular FormulaC56H68Cl4CuN16S4
InChI KeyXRWQTDIELZDCPS-UHFFFAOYSA-J
SMILES[Cl-].[Cl-].[Cl-].[Cl-].CN(C)C(SCC1=CC2=C(C=C1)\C1=N\C3=C4C=CC(CSC(N(C)C)=[N+](C)C)=CC4=C4\N=C5/N=C(/N=C6\N([Cu++]N34)\C(=N/C2=N1)C1=CC(CSC(N(C)C)=[N+](C)C)=CC=C61)C1=C5C=C(CSC(N(C)C)=[N+](C)C)C=C1)=[N+](C)C
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SpecificationsSpecification SheetSpecification Sheet
FormPowder or crystals or crystalline powder
Appearance (Color)Dark blue to blue-green
Assay (Dye)≥50%
lambda-max (UV-Vis)610-635 nm
Solution TestClear blue solution (75 mg in 250 water)
Alcian Blue 8GX is widely utilized as a heteroglycan stain for acidic, neutral, sulfated and phosphate polysaccharides and glycosaminoglycans in tissues. It finds application in both light and electron microscopy. It serves as an adhesive to stick glycol methacrylate sections to glass slides. Due to its large aromatic surface, it is used as a coating agent and modifies the property on the surfaces. It acts as a gelling agent for lubricating fluids and is also used in the modification of carbon paste electrode which promotes redox behavior and stability of electrode.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Alcian Blue 8GX is widely utilized as a heteroglycan stain for acidic, neutral, sulfated and phosphate polysaccharides and glycosaminoglycans in tissues. It finds application in both light and electron microscopy. It serves as an adhesive to stick glycol methacrylate sections to glass slides. Due to its large aromatic surface, it is used as a coating agent and modifies the property on the surfaces. It acts as a gelling agent for lubricating fluids and is also used in the modification of carbon paste electrode which promotes redox behavior and stability of electrode.

Solubility
Soluble in water, ethanol, ethylene glycol and 2-ethoxyethanol. Insoluble in xylene.

Notes
Incompatible with strong oxidizing agents.
RUO – Research Use Only

General References:

  1. Kameyama , A.; Dong, W.; Matsuno, Y. Succinylation-Alcian Blue Staining of Mucins on Polyvinylidene Difluoride Membranes. Methods Mol. Biol. 2015, 1314, 325-331.
  2. Candiano, G.; Santucci, L.; Petretto, A.; Inglese, E.; Bruschi, M.; Ghiggeri, G. E.; Boschetti, E.; Righetti, G. Widening and Diversifying the Proteome Capture by Combinatorial Peptide Ligand Libraries via Alcian Blue Dye Binding. Anal. Chem. 2015, 87 (9), 4814-4820