Thermo Scientific Chemicals

Bestatin hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: J60384.MB
25 mg, Each
Thermo Scientific Chemicals

Bestatin hydrochloride, 98%, Thermo Scientific Chemicals

Catalog number: J60384.MB
25 mg, Each
Quantity
Catalog number: J60384.MB
also known as J60384-MB
Price (USD)
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Chemical Identifiers

CAS
65391-42-6
IUPAC Name
hydrogen (2R,4S,5R)-2,5-diamino-4-hydroxy-2-(2-methylpropyl)-3-oxo-6-phenylhexanoic acid chloride
Molecular Formula
C16H25ClN2O4
InChI Key
JQOATSUOLWQWKR-KHUBKBNHSA-N
SMILES
[H+].[Cl-].CC(C)C[C@](N)(C(O)=O)C(=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1
Form
Powder
Assay from Suppliers CofA
≥97.5%

Description

Bestatin is an inhibitor of amino peptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the amino peptidase activity of LTA4 hydrolase with a Ki value of 201 nM. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation. It does not inhibit carboxypeptidases.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Bestatin is an inhibitor of amino peptidases and a potent, irreversible inhibitor of LTA4 hydrolase. It inhibits the amino peptidase activity of LTA4 hydrolase with a Ki value of 201 nM. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation. It does not inhibit carboxypeptidases.

Solubility
Soluble in water (4 mg/ml, warm), DMSO (>25 mg/ml), methanol, acetic acid, dimethyl formamide, and 100% ethanol.

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents.
RUO – Research Use Only

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