Thermo Scientific Chemicals

Rifampin, Molecular Biology Reagent

Catalog number: J60836.03
1 g, Each
Thermo Scientific Chemicals

Rifampin, Molecular Biology Reagent

Catalog number: J60836.03
1 g, Each
Quantity
Informational:Informational:This chemical may require us to obtain additional information for our regulatory and chemical compliance records. If required, we will contact you for this information once your order is placed.
Catalog number: J60836.03
also known as J60836-03
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Chemical Identifiers

CAS
13292-46-1
IUPAC Name
2,15,17,29-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{[(4-methylpiperazin-1-yl)amino]methylidene}-6,23,27-trioxo-8,30-dioxa-24-azatetracyclo[23.3.1.1⁴,⁷.0⁵,²⁸]triaconta-1,3,5(28),9,19,21,25(29)-heptaen-13-yl acetate
Molecular Formula
C43H58N4O12
InChI Key
FZYOVNIOYYPUPY-UHFFFAOYNA-N
SMILES
COC1C=COC2(C)OC3=C(C)C(O)=C4C(O)=C(NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C)C(=CNN1CCN(C)CC1)C(=O)C4=C3C2=O
Appearance (Color)
Red-brown
Form
Crystals or powder or crystalline powder
Assay from Suppliers CofA
≥95 to ≤103% (dry wt. basis, titration)
Assay from Suppliers CofA
Impurity Rifampicin quinone: ≤ 1.5%
Assay from Suppliers CofA
Related substances other than Rifampicin quinone: ≤1.0%

Description

Antibiotic effective against mycobacteria. Can also inhibit DNA polymeraseRifampin is an antibiotic used in the treatment of tuberculosis and its related microbacterial infections. It is involved in the inhibition of DNA polymerase and RNA polymerase. As an antipruritic agent, it is used in the autoimmune cholestatic liver disease and primary biliary cirrhosis (PBC).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Rifampin is a rifamycin class antibiotic synthesized to resemble the compound isolated from Amycolatopsis rifamycinica
Applications
• Rifampin can be used as a bacteriostatic that prevents RNA and DNA synthesis, particularly in mycobacteria
• It may also act as an antineoplastic, a neuroprotective, and inhibitor of angiogenesis
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only

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