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Adenosine-3',5'-cyclic monophosphate, 98%
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Catalog number J60936.06
also known as J60936-06
Price (USD)/ Each
296.00
-
Quantity:
5 g
Price (USD)/ Each
296.00
Adenosine-3',5'-cyclic monophosphate, 98%
Catalog numberJ60936.06
Price (USD)/ Each
296.00
-
Chemical Identifiers
CAS60-92-4
IUPAC Name(4aR,6R,7R,7aS)-6-(6-amino-9H-purin-9-yl)-2,7-dihydroxy-hexahydro-2λ⁵-furo[3,2-d][1,3,2]dioxaphosphinin-2-one
Molecular FormulaC10H12N5O6P
InChI KeyIVOMOUWHDPKRLL-YPLCUDRINA-N
SMILESNC1=C2N=CN([C@@H]3O[C@@H]4COP(O)(=O)O[C@H]4[C@H]3O)C2=NC=N1
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Specifications
Specification Sheet
Specification SheetProton NMRConforms to structure
Loss on Drying≤10.0%
Assay from Supplier's CofA≥97.5% (HPLC)
Residue on ignition≤0.5%
cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3?: 5?-cyclic monophosphate. In the presence of adenosine 3?:5?-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3?:5?-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3?,5?-cyclic monophosphate.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3′: 5′-cyclic monophosphate. In the presence of adenosine 3′:5′-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3′:5′-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate.
Solubility
Solube in water: 10 mg/mL pH of aqueous solution is approx. 3.0.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
cAMP is used for intracellular signal transduction in many different organisms, conveying the cAMP-dependent pathway. Restoration of several morphological characteristics of normal fibroblasts in sarcoma cells when treated with adenosine-3′: 5′-cyclic monophosphate. In the presence of adenosine 3′:5′-cyclic monophosphate, protein kinase I dissociated into two subunits: a subunit binding adenosine 3′:5′-cyclic monophosphate, and a catalytic subunit. Stimulation of calcium uptake in platelet membrane vesicles by adenosine 3′,5′-cyclic monophosphate.
Solubility
Solube in water: 10 mg/mL pH of aqueous solution is approx. 3.0.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.
RUO – Research Use Only
General References:
- Alfred G. Gilman. A Protein Binding Assay for Adenosine 3':5'-Cyclic Monophosphate. PNAS. 1970, 67 (1) , 305-312.
- B L Brown,; J D Albano,; R P Ekins,; A M Sgherzi. A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate. Biochem J. 1971, 121 (3), 561-562..