TAPS sodium salt is used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. It has been utilized in capillary electrophoresis of such materials as DNA and DNA-dye complexes. Dyes have been separated by planar chromatography with electro osmotic flow with 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated by capillary electrophoresis. It has also been shown to inhibit connexin channel activity. The activity of various mutants of carbonic anhydrase I and carbonic anhydrase II has been studied in a variety of buffers, including TAPS.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
TAPS sodium salt is used in biochemistry and molecular biology. It has a useful pH range of 7.7 - 9.1. It has been utilized in capillary electrophoresis of such materials as DNA and DNA-dye complexes. Dyes have been separated by planar chromatography with electro osmotic flow with 1 mM TAPS in the mobile phase. The stability constants of metal ions with TAPS have been investigated by capillary electrophoresis. It has also been shown to inhibit connexin channel activity. The activity of various mutants of carbonic anhydrase I and carbonic anhydrase II has been studied in a variety of buffers, including TAPS.
Solubility
Soluble in water (333.33 mg/ml).
Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- A.L.Flourat; A.A.M. Peru; A.R.S. Teixeira; F.Brunissen; F.Allais. Chemo-enzymatic synthesis of key intermediates (S)-γ-hydroxymethyl-α,β-butenolide and (S)-γ-hydroxymethyl-γ-butyrolactone via lipase-mediated Baeyer-Villiger oxidation of levoglucosenone. Green Chem. 2015, 17,(1), 404-412.
- Luboslav Starka; Martin Hill; Richard Hampl; Marie-Irene Malewiak; Aida Benalycherif; Robert Morfin; Jaroslav Kolena; Sona Scsukova. Studies on the mechanism of antiglucocorticoid action of 7α-hydroxydehydroepiandrosterone. Collect. Czech. Chem. Commun. 1998, 63,(10), 1683-1698.