Thermo Scientific Chemicals

Citrate, 0.5M buffer soln., pH 3.0

Catalog number: J61391.AK
250 mL, Each
Thermo Scientific Chemicals

Citrate, 0.5M buffer soln., pH 3.0

Catalog number: J61391.AK
250 mL, Each
Quantity
Catalog number: J61391.AK
also known as J61391-AK
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Chemical Identifiers

CAS
6132-04-3
IUPAC Name
trisodium 2-hydroxypropane-1,2,3-tricarboxylate dihydrate
Molecular Formula
C6H9Na3O9
InChI Key
NLJMYIDDQXHKNR-UHFFFAOYSA-K
SMILES
O.O.[Na+].[Na+].[Na+].OC(CC([O-])=O)(CC([O-])=O)C([O-])=O
Comment
Buffer is made by dissolving ingredients in 18.2 megahom, UV treated water, filtered through submicron filter
Form
Clear Liquid
pH
3.0 ± 0.15

Description

Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Citrate is an intermediate in the TCA cycle and fatty acid synthesis. It is an allosteric modulator of acetyl-CoA carboxylase, the enzyme that regulates the conversion of acetyl-CoA to malonyl-CoA. It has anticoagulant activity and is a calcium chelator. Its function is to break protein cross-links; thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies.

Solubility
Fully miscible in water. Insoluble in ethanol.

Notes
Stable under recommended storage conditions. Incompatible with oxidizing agents and heat.
RUO – Research Use Only

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