Thermo Scientific Chemicals

beta-Nicotinamide adenine dinucleotide reduced disodium salt, 97%, Thermo Scientific Chemicals

Catalog number: J61638.06
5 g, Each
Thermo Scientific Chemicals

beta-Nicotinamide adenine dinucleotide reduced disodium salt, 97%, Thermo Scientific Chemicals

Catalog number: J61638.06
5 g, Each
Quantity
Catalog number: J61638.06
also known as J61638-06
Price (USD)
Quantity
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Chemical Identifiers

CAS
606-68-8
IUPAC Name
disodium [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl ({[(2R,3S,4R,5R)-5-(3-carbamoyl-1,4-dihydropyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphonato}oxy)phosphonate
Molecular Formula
C21H27N7Na2O14P2
InChI Key
QRGNQKGQENGQSE-WUEGHLCSSA-L
SMILES
[Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)N2C=NC3=C(N)N=CN=C23)[C@@H](O)[C@H]1O
Molar extinction coefficient (molar absorptivity)
340nm: ≥6000 L/(mole cm)
Form
Powder
Water Content (Karl Fischer Titration)
≤8%
Molar extinction coefficient (molar absorptivity)
260nm: ≥14000 L/(mole cm)
Appearance (Color)
White to yellow

Description

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases). As a reagent, NADH can be used in enzyme cycling assays to amplify detection of activity of biologically relevant enzymes or metabolites present in low concentrations.

Solubility
It is soluble in water.

Notes
Store with desiccant. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature -20°C Light sensitive. Hygroscopic.
RUO – Research Use Only

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