Thermo Scientific Chemicals

Histamine, Thermo Scientific Chemicals

Catalog number: J61727.06
5 g, Each
Thermo Scientific Chemicals

Histamine, Thermo Scientific Chemicals

Catalog number: J61727.06
5 g, Each
Quantity
Catalog number: J61727.06
also known as J61727-06
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Chemical Identifiers

CAS
51-45-6
IUPAC Name
2-(1H-imidazol-5-yl)ethan-1-amine
Molecular Formula
C5H9N3
InChI Key
NTYJJOPFIAHURM-UHFFFAOYSA-N
SMILES
NCCC1=CN=CN1
Assay from Supplier's CofA
≥97.0%
Appearance (Color)
White to pale yellow to pale brown
Loss on Drying
≤3.0%
Form
Powder or crystals or crystalline powder

Description

Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Histamine inhibits the synthesis of IL-2 and γ-IFN in peripheral blood mononuclear cells and lipopolysaccharide-induced synthesis of TNF-α in monocytes via H2 receptor activation. It is a powerful stimulant of gastric secretion, a constrictor of bronchial smooth muscle, a vasodilator, and also a centrally acting neurotransmitter.

Solubility
Soluble in water, alcohol, and hot chloroform.

Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C Hygroscopic. Handle and store under inert gas. Air sensitive.
RUO – Research Use Only

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