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Tolnaftate, Thermo Scientific Chemicals
Antifungal agent
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Catalog number J61834.03
also known as J61834-03
Price (USD)/ Each
53.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
63.00 Save 9.35 (15%)
-
Quantity:
1 g
Price (USD)/ Each
53.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
63.00 Save 9.35 (15%)
Tolnaftate, Thermo Scientific Chemicals
Catalog numberJ61834.03
Price (USD)/ Each
53.65
Special Offer
Online exclusive
Ends: 31-Dec-2024
63.00 Save 9.35 (15%)
-
Chemical Identifiers
CAS2398-96-1
IUPAC NameN-methyl-N-(3-methylphenyl)-1-(naphthalen-2-yloxy)methanethioamide
Molecular FormulaC19H17NOS
InChI KeyFUSNMLFNXJSCDI-UHFFFAOYSA-N
SMILESCN(C(=S)OC1=CC=C2C=CC=CC2=C1)C1=CC=CC(C)=C1
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to yellow
Assay (unspecified)≥97.5%
FormPowder
Melting Point110-113°C
Tolnaftate is used to study the mechanism of ergosterol (sterol) biosynthesis at the rate-limiting step of squalene epoxidase inhibition. Tolnaftate is clinically used to treat cutaneous infections such as athlete?s foot, jock itch, and ringworm1. It also has been used as a comparator compound for antifungal efficiency studies.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
Soluble in chloroform at 50 mg/ml. Sparingly soluble in ethanol or methanol
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: 2 - 8°C
RUO – Research Use Only
General References:
- Craig Knox et. al. DrugBank 3.0: a comprehensive resource for omics research on drugs. Nucleic Acids Research. 2011, 39, D1035-D1041.
- J Pannu et. al. NB-002, a novel nanoemulsion with broad antifungal activity against dermatophytes, other filamentous fungi, and Candida albicans. Antimicrobial Agents and Chemotherapy. 2011, 53, (8), 3273-3279.