General Description

• Elastase is a serine protease that can hydrolyze elastin, a specific protein of elastic fibers

Application

• Elastase, porcine pancreas has been used in cell culture techniques, ELISA assays, and in experiments to measure the inhibitory activity of elastase

• Since elastin is found in the fibers of connective tissues, elastase is commonly used to dissociate tissues that contain extensive intercellular fiber networks

• It is typically used with other enzymes, including collagenase, trypsin, and chymotrypsin

• Elastase enzyme is isolated from porcine pancreas and can be used alone or combined with other proteases for protein analysis by mass spectrometry and other applications, including membrane protein solubilization and protein sequence studies

• This compound also hydrolyzes amides and esters such as N-Benzoyl-L-alanine methyl ester