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DL-Aminoglutethimide, 99%, Thermo Scientific Chemicals
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Catalog number J62182.14
also known as J62182-14
Price (USD)/ Each
354.00
-
Quantity:
25 g
Price (USD)/ Each
354.00
DL-Aminoglutethimide, 99%, Thermo Scientific Chemicals
Catalog numberJ62182.14
Price (USD)/ Each
354.00
-
Specifications
Chemical Name or MaterialDL-Aminoglutethimide
CAS125-84-8
Health Hazard 1H315-H319-H335
Health Hazard 2GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
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Aminoglutethimide is used to decrease the production of sex hormones and suppress the growth of tumors that need sex hormones to grow. It blocks the production of steroids derived from cholesterol and is clinically used in the treatment of Cushing's syndrome and metastatic breast cancer. It is also a drug of abuse by body builders.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water (2 mg/ml at 20°C), methanol (50 mg/ml), ethanol (7 mg/ml at 25°C), DMSO (20 mg/ml at 25°C), and chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
Soluble in water (2 mg/ml at 20°C), methanol (50 mg/ml), ethanol (7 mg/ml at 25°C), DMSO (20 mg/ml at 25°C), and chloroform.
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Keep away from strong oxidizing agents.
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
General References:
- Imming P.; Sinning C.; Meyer A. Drugs, their targets and the nature and number of drug targets. Nat Rev Drug Discov.2006, 5, (10), 821-34.
- Siraki AG.; Bonini MG.; Jiang J.; Ehrenshaft M.; Mason RP. Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. Chem Res Toxicol.2007, 20, (7), 1038-45.