A calcium channel antagonist with potent antioxidant activityAmlodipine is an L-type calcium channel protein inhibitor and blocker. It is used in combination with the angiotensin receptor blocker olmesartan. Further, it acts as a dihydropyridine calcium channel blocker. It is used as an anti-hypertensive. It is involved in the treatment of angina and to lower blood pressure. In addition to this, it is used to prevent chest pain and in coronary artery disease.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in dimethyl sulfoxide, ethanol, water, dimethyl formamide, acetone, chloroform, ethyl acetate and methanol.
Notes
Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- Akamine, Y.; Uehara, H.; Miura, M.; Yasui-Furukori, N.; Uno, T. Multiple inductive effects of carbamazepine on combined therapy with paliperidone and amlodipine. J. Clin. Pharm. Ther. 2015, 40 (4), 480-482.
- Norouzi, P.; Gupta, V. K.; Larijani, B.; Rasoolipour, S.; Faridbod, F.; Ganjali, M. R. Coulometric differential FFT admittance voltammetry determination of Amlodipine in pharmaceutical formulation by nano-composite electrode. Talanta 2015, 131, 577-584.