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Brefeldin A, 98%, Thermo Scientific Chemicals
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Catalog number J62340.MA
also known as J62340-MA
Price (USD)/ Each
127.65
Online exclusive
142.00 Save 14.35 (10%)
-
Quantity:
10 mg
Price (USD)/ Each
127.65
Online exclusive
142.00 Save 14.35 (10%)
Brefeldin A, 98%, Thermo Scientific Chemicals
Catalog numberJ62340.MA
Price (USD)/ Each
127.65
Online exclusive
142.00 Save 14.35 (10%)
-
Chemical Identifiers
CAS20350-15-6
IUPAC Name(1S,6S,11aS,13S,14aR)-1,13-dihydroxy-6-methyl-1H,4H,6H,7H,8H,9H,11aH,12H,13H,14H,14aH-cyclopenta[f]oxacyclotridecan-4-one
Molecular FormulaC16H24O4
InChI KeyKQNZDYYTLMIZCT-PNFJWZTBSA-N
SMILESC[C@H]1CCC\C=C\[C@@H]2C[C@H](O)C[C@H]2[C@@H](O)\C=C\C(=O)O1
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Specifications
Specification Sheet
Specification SheetFormCrystals or powder or crystalline powder or granules
Appearance (Color)White to pale yellow
Assay (HPLC)≥97.5%
Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.
Solubility
Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
Brefeldin A mediated apoptosis has been observed in human tumor cellsIt is an antibiotic used in cell culture and to inhibit protein secretion in mammalian and other eukaryotic cells by interfering with the function of the Golgi apparatus.
Solubility
Soluble in dimethylsulfoxide, dichloromethane and ethanol. Slightly soluble in water.
Notes
Store in cool place. Incompatible with strong oxidizing agents.
RUO – Research Use Only
General References:
- Wase, N.; Tu, B.; Black, P. N.; DiRusso, C. C. Phenotypic screening identifies Brefeldin A/Ascotoxin as an inducer of lipid storage in the algae Chlamydomonas reinhardtii. Algal Res. 2015, 11, 74-84.
- Fuchs, M.; Fîrstner, A. trans-Hydrogenation: Application to a Concise and Scalable Synthesis of Brefeldin A. Angew. Chem. 2015, 54 (13), 3978 -3982.