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(+)-1-Deoxynojirimycin, Thermo Scientific Chemicals
Catalog number J62602.MC
also known as J62602-MC
Price (USD)/ Each
506.65
Online exclusive
563.00 Save 56.35 (10%)
-
Quantity:
100 mg
Price (USD)/ Each
506.65
Online exclusive
563.00 Save 56.35 (10%)
(+)-1-Deoxynojirimycin, Thermo Scientific Chemicals
Catalog numberJ62602.MC
Price (USD)/ Each
506.65
Online exclusive
563.00 Save 56.35 (10%)
-
Chemical Identifiers
CAS19130-96-2
IUPAC Name(2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular FormulaC6H13NO4
InChI KeyLXBIFEVIBLOUGU-JGWLITMVSA-N
SMILESOC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O
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Specifications
Specification Sheet
Specification SheetAppearance (Color)White to off-white
Purity≥95.0%
Proton NMRConforms
FormPowder
An alpha-glucosidase inhibitor. Interferes with normal processing of N-linked glycoproteins.(+)-1-Deoxynojirimycin acts as an inhibitor of alfa-glucosidase I and II and maltase-glucoamylase. It also inhibits mammalian glucosidase, intestinal and lysosmal, beta-glucosidase from sweet almonds, pancreatic alfa-amylase and amyloglucosidase. Further, it serves as a enzyme enhancer for the treatment of Fabry and Pompe disease.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water, dimethyl sulfoxide and methanol.
Notes
Incompatible with strong acids and strong bases.
Soluble in water, dimethyl sulfoxide and methanol.
Notes
Incompatible with strong acids and strong bases.
RUO – Research Use Only
General References:
- Liu, C.; Xiang, W.; Yu, Y.; Shi, Z. Q.; Huang, X. Z.; Xu, L. Comparative analysis of 1-deoxynojirimycin contribution degree to alpha-glucosidase inhibitory activity and physiological distribution in Morus alba L. Ind. Crops Prod. 2015, 70, 309-315.
- Park, S. H.; Kim, J. Y.; Kim, J. S.; Jung, C.; Song, D. K.; Ham, W. H. 1,3-Oxazine as a chiral building block used in the total synthesis of (+)-1-deoxynojirimycin and (2R,5R)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine. Tetrahedron: Asymmetry 2015, 26 (12-13), 657-661.