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Gentamicin sulfate, 600 I.U./mg, Thermo Scientific Chemicals
Catalog number: J62834.03
1 g, Each
Thermo Scientific Chemicals
Gentamicin sulfate, 600 I.U./mg, Thermo Scientific Chemicals
Catalog number: J62834.03
1 g, Each
Quantity
Catalog number: J62834.03
also known as J62834-03
Price (USD)
34.00
Each
Quantity
-
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Chemical Identifiers
CAS
1405-41-0
IUPAC Name
(2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-(aminomethyl)oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-(methylamino)ethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; (2R,3R,4R,5R)-2-{[(1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2R,3R,6S)-3-amino-6-[(1R)-1-aminoethyl]oxan-2-yl]oxy}-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol; sulfuric acid
Molecular Formula
C60H125N15O25S
InChI Key
RDEIXVOBVLKYNT-HDZPSJEVSA-N
SMILES
OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O)OC[C@]1(C)O.CN[C@@H]1[C@@H](O)[C@@H](O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@@H](CC[C@H]3N)[C@@H](C)N)[C@@H]2O)OC[C@]1(C)O.CN[C@H](C)[C@@H]1CC[C@@H](N)[C@@H](O[C@@H]2[C@@H](N)C[C@@H](N)[C@H](O[C@H]3OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)O1
Specifications
Specification SheetAppearance (Color)
White to cream
pH
3.5 to 5.5
Potency
≥ 590 µ/ mg (fry basis)
Assay (special)
Bacterial endotoxin: ≤ 0.71 IU/mg
Assay (special)
Related substances: C1a: 10 to 35%; C2a+: 25 to 55%; C2b + C2: 25 to 50 %
Description
Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses. This compound is a mixture of Gentamycin c1, c1a and c2.
Research Use only: Not intended for animal or human diagnostic or therapeutic use.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Gentamicin sulfate is a bactericidal aminoglycoside antibiotic which shows activity against Gram-negative bacteria
• It works by inhibiting protein biosynthesis through binding the bacterial ribosome 30S subunit
Applications
• Gentamicin sulfate has been used in studies to determine wound healing due to its antibiotic and antifungal properties
• It has laboratory research applications in the study of a number of clinical conditions, including actinomycotic infection, appendicitis, cystic fibrosis, osteomyelitis, pelvic inflammatory disease, plague, gonorrhea, and tularemia
WARNING: Reproductive Harm - www.P65Warnings.ca.gov
RUO – Research Use Only
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