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Capsazepine, 98+%, Thermo Scientific Chemicals
Catalog number: J63055.MF
50 mg, Each
Thermo Scientific Chemicals
Capsazepine, 98+%, Thermo Scientific Chemicals
Catalog number: J63055.MF
50 mg, Each
Quantity
Catalog number: J63055.MF
also known as J63055-MF
Price (USD)
1,393.00
Each
Quantity
-
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Chemical Identifiers
CAS
138977-28-3
IUPAC Name
N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine-2-carbothioamide
Molecular Formula
C19H21ClN2O2S
InChI Key
DRCMAZOSEIMCHM-UHFFFAOYSA-N
SMILES
OC1=CC2=C(CN(CCC2)C(=S)NCCC2=CC=C(Cl)C=C2)C=C1O
Specifications
Specification SheetAppearance (Color)
Powder
Assay (HPLC)
≥ 98.0%
Form
Pale cream to cream
Proton NMR
Conforms to structure
Solution Test
Soluble in DMSO at 100mM
Description
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.
Solubility
Soluble in ethanol or DMSO
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
Capsazepine is shown to inhibit the development of mechanical hyperalgesia induced by intraplanar capsaicin injection. Capsazepine is described to block Resiniferatoxin (sc-24015)- and Capsaicin-induced contractions of guinea pig treacheal smooth muscle. Studies investigating the function of the VR1 (TRPV1 receptor) have employed Capsazepine as a tool for perturbing systemic neuronal response to Capsaicin.
Solubility
Soluble in ethanol or DMSO
Notes
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Recommended storage temperature: -20°C. Keep away from strong oxidizing agents.
RUO – Research Use Only
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