Search Thermo Fisher Scientific
Element Search
Structure Search
Thermo Scientific Chemicals
Fibrinogen, Bovine
Fibrinogen (CAS # 9001-32-5) is a glycoprotein produced in the vertebrate liver that aids in clot formation.
Have Questions?
Change view
Catalog number J63276.03
also known as J63276-03
Price (USD)Contact Us
-
Quantity:
1g
Chemical Identifiers
CAS9001-32-5
Specifications
Specification Sheet
Specification SheetAssay from Supplier's CofAClottable Protein (biuret): ≥90%
Appearance (Color)White
Assay (unspecified)Solubility: 3% w/v in DIH2O
pH5.0-7.0
FormPowder
View more
A soluble plasma glycoprotein, produced by the liver, that is converted by thrombin into fibrin during the blood coagulation process. Fibrinogen is a natural blood protein involved in the coagulation process. It is used instead of traditional sources of fibrinogen such as the blood products, fresh frozen plasma and cryoprecipitate. It helps in blood clot formation.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Fibrinogen exists in blood as a dimer of three bonded, non-identical chains, FGA, FGG, and FGB
• Fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots
Application
• Fibrinogen can be used in a laboratory setting to form polymer hydrogels, particularly for use as a tissue scaffold
• Fibrinogen may be useful in the research of neurodegeneration and brain injury; some evidence shows that it has a signaling role in neural progenitor cells
RUO – Research Use Only
General References:
- Jira W, Schwägele F. A sensitive HPLC-MS/MS method for the simultaneous detection of microbial transglutaminase, and bovine and porcine fibrinogen/thrombin in restructured meat. Food Chem. 2017 Dec 15;237:841-848. doi: 10.1016/j.foodchem.2017.06.030. Epub 2017 Jun 12. PMID: 28764076.
- Kargl R, Bračič M, Resnik M, Mozetič M, Bauer W, Stana Kleinschek K, Mohan T. Affinity of Serum Albumin and Fibrinogen to Cellulose, Its Hydrophobic Derivatives and Blends. Front Chem. 2019 Sep 6;7:581. doi: 10.3389/fchem.2019.00581. PMID: 31552215; PMCID: PMC6743410.