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Tamoxifen, 98%, Thermo Scientific Chemicals
Catalog number: J63509.03
1 g, Each
Thermo Scientific Chemicals
Tamoxifen, 98%, Thermo Scientific Chemicals
Catalog number: J63509.03
1 g, Each
Quantity
Catalog number: J63509.03
Price (USD)
Special offer:
175.65 185.65 Online priceSave 10.00 (5%)
Ends: 15-Oct-2024
Each
Quantity
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Chemical Identifiers
CAS
10540-29-1
Specifications
Specification SheetForm
Powder
Proton NMR
Conforms to stucture
Appearance (Color)
White to pale cream
Assay from Supplier's CofA
≥97.5%
Description
Inhibitor of protein kinase C and induces apoptosis in cancer cells. It is utilized in the study on lipopolysaccharide (LPS)-induced microglial activation to know its effect.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- Tamoxifen is a tertiary aminobenzene that acts by competitively binding and antagonizing estrogen receptors to reduce DNA synthesis
- When estradiol cannot bind estrogen receptors, the DNA response element is not activated
- Tamoxifen upregulates the production of TGFb and slows tumor growth
- Tamoxifen inhibits the production of IGF-1, a stimulator of tumor growth
Application
- Tamoxifen may be useful in the study of tumorigenesis, growth, and inflammation
- It is suitable for in vitro experiments
WARNING: Cancer – www.P65Warnings.ca.gov
RUO – Research Use Only
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